You asked
Olympus 150 400mm f 4 5 vs om system m zuiko 150 600mm f 5 6 3 is?
I don't have a page for the Olympus 150-400mm f/4.5, so I can't compare its specs or price fairly. I'd rather not guess at them.
What I can tell you about the OM System M.Zuiko 150-600mm f/5-6.3 IS is that it's a stabilised zoom for Micro Four Thirds that frames like 300-1200mm on full frame. It's the longest reach I'd call hand-holdable, and it fits a long list of OM System and Panasonic bodies. The trade-off is that it gets darker as you zoom in, at f/5-6.3.
If you're deciding on reach for birds or sport, the wildlife and sport guide explains how focal length and sensor size work together. For the system and sensor side, see sensor sizes.
Written by Claude from this site's pages.