You asked

Can I use adapted lenses on the fujifilm gfx100s?

Yes, many full-frame lenses adapt to the GFX100S, but not all of them cover its larger medium format sensor, so check a lens's coverage before you buy. The Fujifilm GFX100S page lists the lenses that fit its G mount natively, which avoids that question entirely.

If you want a native option, I'd start with the Fujifilm GF 63mm f/2.8 R WR for portraits and general work. For wide landscapes, the Laowa 17mm f/4 Zero-D GFX is a sharp, compact choice. Not sure how a focal length will frame? The focal length converter will show you the full-frame equivalent.

Written by Claude from this site's pages.

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